현재, 미녹시딜은 FDA가 MPHL에 대해 승인한 유일한 치료법입니다.
치료 개시 6개월에서 12개월 사이에 눈에 띄게 개선이 이루어집니다. 최대의 효과를 얻기 위해서는 2년의 사용기간이 필요하며, 지속적인 사용이 권장됩니다. 치료 중단은 바람직하지 않은 결과를 초래할 수 있습니다.
피나스테리드
권장 복용량은 얼마인가요?
평균 복용량은 1mg/일이지만, 0.2mg/일의 복용량으로 유의미한 개선이 관찰됩니다.
다른 의약품과 반응할 가능성이 있는가요?
의약품의 상호작용은 알려진 바 없습니다.
피나스테리드의 사용을 억제해야 하는 질병이나 조건이 있는가요?
피나스테리드는 임산부와 간 질환 환자가 사용해서는 안 됩니다.
미녹시딜
미녹시딜은 어떻게 작용하는가요?
미녹시딜의 작용방식은 아직 불분명합니다. 그것은 모낭 소형화를 방지하거나 지연시킬 수 있습니다.
미녹시딜의 권장 복용량은 얼마인가요?
MPHL에서 5% 용액은 2% 용액보다 우수합니다. FPHL에서 1%와 2% 미녹시딜 용액이 모두 모발 수를 증가시킵니다. 권장 복용량은 2%와 5% 모두 1ml(25방울)이거나 매일 두 번 바르는 거품의 모자 절반 분량입니다.
미녹시딜 치료 기간은 어떻게 되나요?
미녹시딜 치료는 장기적입니다. 미녹시딜을 중단하면 4개월에서 6개월 이내에 미녹시딜에 의존하는 모든 모발이 탈모됩니다.
미녹시딜의 부작용은 무엇인가요?
미녹시딜의 부작용으로는 피부 자극, 얼굴과 손의 다모증, 심계항진증 등이 있습니다. 5%의 프로필렌 글리콜 무염 폼 조제품은 잠재적으로 덜 자극적이고 덜 불쾌합니다. 다모증은 완전히 원상회복시킬 수 있습니다.
미녹시딜의 사용을 억제해야 하는 질병이나 조건이 있는가요?
미녹시딜은 임산부나 간질환 환자에게 사용해서는 안 됩니다. 심혈관 질환 환자에게도 주의해서 사용해야 합니다.
두타스테라이드
두타스테라이드는 어떻게 작용하는가요?
두타스테라이드는 타입 I과 II 5α-감산제를 모두 억제하여 결과적으로 모발 수와 모발 무게를 증가시키고, 텔로겐 모발에 대한 아나겐 비율을 개선하여 두피 범위를 개선시킵니다.
권장 복용량은 얼마인가요?
MPHL의 진행을 개선하거나 방지하려면 두타스테라이드 0.5 mg/일의 투여가 적당하다고 간주됩니다.
두타스테라이드의 부작용은 무엇인가요?
두타스테라이드의 부작용은 발기부전, 성욕 감소, 유방 유연화, 유방확대, 사정 射精장애 등입니다.
두타스테라이드의 사용을 억제해야 하는 질병이나 조건이 있는가요?
반감기가 길기 때문에 두타스테라이드로 치료를 받고 있는 남성들은 헌혈을 해서는 안 됩니다. 두타스테라이드는 효과적인 피임을 하지 않는 성숙한 여성들에게 사용되어서는 안 됩니다. 또한 이 약을 복용하는 동안 간 기능을 관찰해야 합니다.
PG 경로는 PGE2와 PGF2α가 모발 성장을 촉진하는 반면 PGD2는 모발 성장을 억제하기 때문에 모발 성장과 밀접한 관련이 있습니다. AGA가 가벼운 남성의 경우 PGF2 아날로그인 0.1%의 라타노프로스트가 모발 밀도와 착색을 크게 증가시키는 것으로 나타났습니다.
케토코나졸은 모발 성장을 촉진시킬 수 있는 피부염과 비듬의 치료에 효과적인 항균제입니다. 일반적으로 다른 AGA 치료와 함께 활용됩니다.
혈소판이 풍부한 혈장(PRP)은 혈소판이 있는 혈장을 스스로 제조한 것입니다. PRP는 성형수술과 상처치유와 관련해서 자주 사용됩니다. 일부 모발 이식 외과의들은 모낭을 PRP에 저장하거나 이식 전 두피에 PRP를 주입하여 PRP를 사용합니다. 모발성장의 자극에 대한 직접적인 영향을 뒷받침하는 데이터는 제한적입니다.
MPHL과 FPHL의 치료를 위해 FDA가 승인한 모발 맥스 레이저 빗 등 LLLT를 사용하는 여러 가지 종류의 제품이 부속 치료에 이용 가능합니다. LLLT, 특히 5mW에서의 650-900nm 파장은 독립 치료 또는 부속 치료로서 어느 한 상태에 대해서도 효과적인 대체 치료로 간주될 수 있습니다.
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