5a-Reductase inhibitors part 2
They are effective in treating AGA and promoting hair regrowth. They can be given orally, topically and recently through mesotherapy.
Many clinical trials for treating AGA and BPH documented safety and tolerability of 5aRIs. While many users has experienced minimal or no obvious side effects, for some patients the adverse side effects are loss of libido, diminished libido, erectile dysfunction, ejaculatory dysfunction, anxiety, depression, and in some cases contemplating suicide.
Although patients treated with 5aRIs have an increased incidence of sexual adverse events, these events decrease if discontinued or over time with continued therapy. There has been a rising concern about uncommon persistent sexual and nonsexual side-effects in a subset of younger men.